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Swedish Match has also urged the FDA to replace another 30-year old deceptive warning, This product is not a safe alternative to cigarettes, with this: No tobacco product is safe, but this product presents substantially lower risks to health than cigarettes. The replacement warning is identical to a change requested by RJ Reynolds four years ago in a citizen petition filed with the FDA

Direct comparative studies are needed to rigorously assess the relative cardiovascular risk profile of nicotine pouches versus cigarettes, E-cigarettes, and traditional smokeless tobacco, using both biomarker and clinical endpoints

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